Chronic granulomatous disease mimicking early-onset Crohn’s disease with cutaneous manifestations

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Chronic granulomatous disease mimicking early-onset Crohn’s disease with cutaneous manifestations

BACKGROUND Chronic granulomatous disease is a rare inherited disorder of the innate immune system. In patients with a clinical history of recurrent or persistent infections, especially infections caused by uncommon species, chronic granulomatous disease should be considered. CASE PRESENTATION We report the case of a 5-year-old boy with a presumptive diagnosis of Crohn's disease with extrainte...

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gastrointestinal manifestations of patients with chronic granulomatous disease

chronic granulomatous disease (cgd) represents a group of inherited disorders of phagocytic system, manifesting recurrent infections at different sites. the present study was accomplished in order to determine the gastrointestinal manifestations of cgd patients. fifty-seven patients (38 males and 19 females) with cgd, who had been referred to three immunodeficiency referral centers in iran, wer...

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Very Early-Onset Inflammatory Manifestations of X-Linked Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is a rare primary immune deficiency caused by mutations in genes coding for components of the nicotinamide adenine dinucleotide phosphate oxidase, characterized by severe and recurrent bacterial and fungal infections, together with inflammatory complications. Dysregulation of inflammatory responses are often present in this disease and may lead to granulomato...

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ژورنال

عنوان ژورنال: BMC Pediatrics

سال: 2014

ISSN: 1471-2431

DOI: 10.1186/1471-2431-14-156